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恶性腹膜细胞学检查作为Ⅰ期子宫内膜癌的预后指标

Malignant peritoneal cytology as prognostic indicator in stage I endometrial cancer.

作者信息

Yazigi R, Piver M S, Blumenson L

出版信息

Obstet Gynecol. 1983 Sep;62(3):359-62. doi: 10.1097/00006250-198309000-00019.

DOI:10.1097/00006250-198309000-00019
PMID:6877692
Abstract

The prognostic significance of malignant peritoneal cytology was evaluated in 93 patients with stage I endometrial cancer seen at Roswell Park Memorial Institute. Eighty-three patients (89%) had negative cytologic samples and ten (11%) had positive cytology for neoplastic cells. All patients were followed for a minimum of ten years or until dead from cancer or intercurrent disease. No patient received treatment for positive cytology. There was one recurrence in the patients with positive cytology (10%), and six recurrences in the negative group (7%). The actuarial survival rate at five and ten years for patients with negative cytology was 93.9 and 92.5%, respectively. For patients with positive cytology, the survival was 87.5% at both time intervals. No significant difference was found between the groups. Malignant peritoneal cytology does not seem to be a prognostic indicator in stage I endometrial cancer.

摘要

在罗斯韦尔帕克纪念研究所就诊的93例I期子宫内膜癌患者中,评估了恶性腹腔细胞学检查结果的预后意义。83例患者(89%)细胞学检查样本为阴性,10例(11%)癌细胞学检查为阳性。所有患者至少随访10年,或直至死于癌症或并发疾病。没有患者因细胞学检查阳性而接受治疗。细胞学检查阳性的患者中有1例复发(10%),阴性组有6例复发(7%)。细胞学检查阴性的患者5年和10年的精算生存率分别为93.9%和92.5%。对于细胞学检查阳性的患者,两个时间点的生存率均为87.5%。两组之间未发现显著差异。恶性腹腔细胞学检查似乎不是I期子宫内膜癌的预后指标。

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