Simultaneous determination of diphenylhydantoin, mephobarbital, carbamazepine, phenobarbital and primidone in serum using direct chemical ionization mass spectrometry.
作者信息
Truscott R J, Burke D G, Korth J, Halpern B, Summons R
出版信息
Biomed Mass Spectrom. 1978 Aug;5(8):477-82. doi: 10.1002/bms.1200050803.
PMID:687779
Abstract
A quantitative method for the simultaneous determination of five anticonvulsants in serum has been developed using chemical ionization mass spectrometry without prior chromatographic separation. The technique was shown to be rapid, simple and sensitive, allowing the routine analysis of 50 microliter of serum with good within-day and day-to-day precision.
摘要
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