库尔德犹太人β⁰地中海贫血中β mRNA的缺失。
Absence of beta mRNA in beta0-thalassemia in Kurdish Jews.
作者信息
Ramirez F, Starkman D, Bank A, Kerem H, Cividalli G, Rachmilewitz E A
出版信息
Blood. 1978 Oct;52(4):735-9.
PMID:687828
Abstract
We report the characterization of the amount of beta mRNA in a Kurdish Jewish population with beta0-thalassemia using the same methods employed for characterization of the Catania and Ferrara beta0 patients. We found very low amounts of beta mRNA sequences, consistent with the presence of beta0-thalassemia of the beta mRNA-negative population type. In addition, no globin gene deletion was detected that could account for the absence of beta mRNA.
摘要
我们报告了使用与卡塔尼亚和费拉拉β0患者特征分析相同的方法，对患有β0地中海贫血的库尔德犹太人群体中β mRNA量的特征分析。我们发现β mRNA序列的量非常低，这与β mRNA阴性群体类型的β0地中海贫血的存在一致。此外，未检测到可解释β mRNA缺失的珠蛋白基因缺失。
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