A review of the current impact of measles in the People's Republic of China.

Before the vaccine era, epidemics of measles occurred in alternate years on the mainland of China. During epidemic years the annual incidence was as high as 1,000-5,000 cases/100,000 population, with a fatality rate of 1% to 2%. In 1965, when highly attenuated measles vaccine was developed in China, a vaccination campaign was launched throughout the country. In its early years, the immunization program was not implemented simultaneously at all places, and outbreaks that continued to occur in some areas resulted in a moderate local incidence of measles despite a decline in the overall incidence. From the late 1970s on, stronger measures were taken by local health authorities with regard to measles vaccination. By 1980 the incidence had dropped further; in that year the number of reported cases was 570,037, with 3,862 deaths. Both morbidity and mortality related to measles dropped drastically after vaccination from levels in the prevaccine era, but measles still accounts for an appreciable proportion of all cases of infectious disease.