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拉丁美洲6至12个月大儿童接种麻疹疫苗后的血清转化率及诱导产生的麻疹抗体滴度

Seroconversion rates and measles antibody titers induced by measles vaccination in Latin American children six to 12 months of age.

出版信息

Rev Infect Dis. 1983 May-Jun;5(3):596-605.

PMID:6879022
Abstract

A collaborative study was conducted to determine how 2,042 infants responded serologically to measles vaccination in six study areas and to help define the optimal age for measles vaccination in children of Latin America. The results suggest that local factors affect the seroconversion rate and that a success rate of 90% can be attained if initial vaccination is given at nine to 11 months of age, depending on the area. Post-vaccination titers also varied, and higher titers were generally observed in groups with higher seroconversion rates.

摘要

开展了一项合作研究,以确定2042名婴儿在六个研究地区对麻疹疫苗的血清学反应,并帮助确定拉丁美洲儿童麻疹疫苗接种的最佳年龄。结果表明,当地因素会影响血清转化率,并且根据地区不同,如果在9至11个月龄时进行初次接种,血清转化率可达90%。接种疫苗后的滴度也有所不同,血清转化率较高的组中通常观察到较高的滴度。

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Seroconversion rates and measles antibody titers induced by measles vaccination in Latin American children six to 12 months of age.拉丁美洲6至12个月大儿童接种麻疹疫苗后的血清转化率及诱导产生的麻疹抗体滴度
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