Ost A, Lagerlöf B, Sundström C, Lindström P, Gyllenhammer H, Engstedt L, Skoog L
Scand J Haematol. 1983 Sep;31(3):257-66. doi: 10.1111/j.1600-0609.1983.tb00650.x.
The Leukaemia Group of Middle Sweden recently started a new multicentre study of treatment of adult patients with acute leukaemia from 6 centres. The criteria for the diagnosis, subclassification, degree of leukaemic bone marrow infiltration, remission and relapse are to be used by the morphologists of 6 different pathology departments. The reproducibility of the criteria has been studied by 3 of the morphologists concerned, in a retrospective review of a strictly consecutive series of 79 adult patients treated at Södersjukhuset, Stockholm, Sweden, in the years 1978 to 1981. The results show that the reproducibility of the criteria and the concordance of the morphologists when using them increased when the criteria were made more detailed and precise.
瑞典中部白血病研究小组最近启动了一项新的多中心研究,该研究针对来自6个中心的成年急性白血病患者进行治疗。6个不同病理科的形态学家将使用诊断、亚分类、白血病骨髓浸润程度、缓解和复发的标准。其中3位相关形态学家对1978年至1981年期间在瑞典斯德哥尔摩南医院接受治疗的79例成年患者的严格连续系列病例进行了回顾性研究,以此来研究这些标准的可重复性。结果表明,当标准制定得更加详细和精确时,标准的可重复性以及形态学家使用这些标准时的一致性均有所提高。