Harding T H, Wiley R W, Kirby A W
Science. 1983 Sep 9;221(4615):1076-8. doi: 10.1126/science.6879206.
Visually evoked responses to counterphased gratings were recorded from the cat visual cortex before and after physostigmine administration. Physostigmine markedly reduced the responses to low spatial frequencies, but minimally affected the response to high frequencies. This effect is considered cholinergic since it could be reversed by atropine. These results support at least a two-channel model of spatial frequency responsivity.
在给予毒扁豆碱前后，记录猫视觉皮层对反相光栅的视觉诱发电反应。毒扁豆碱显著降低了对低空间频率的反应，但对高频率反应的影响极小。由于阿托品可逆转这种效应，所以认为这种作用是胆碱能性的。这些结果至少支持空间频率反应性的双通道模型。
