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二异丙基氟磷酸酯对猫视觉系统空间频率反应性的影响。

The effects of diisopropylfluorophosphate on spatial frequency responsivity in the cat visual system.

作者信息

Harding T H, Kirby A W, Wiley R W

出版信息

Brain Res. 1985 Jan 28;325(1-2):357-61. doi: 10.1016/0006-8993(85)90340-3.

DOI:10.1016/0006-8993(85)90340-3
PMID:3978426
Abstract

Visual-evoked responses to counterphased gratings were recorded from area 17 of cat visual cortex before and after diisopropylfluorophosphate (DFP) administration. DFP produced effects similar to those obtained following physostigmine sulfate administration, in that responses to low spatial frequencies were preferentially reduced. The time course of the effects was quite different for the two types of drugs, and for high doses of DFP responses to all spatial frequencies were approximately uniformly depressed or abolished.

摘要

在给予二异丙基氟磷酸酯(DFP)之前和之后,从猫视觉皮层17区记录了对反相光栅的视觉诱发电反应。DFP产生的效应与给予硫酸毒扁豆碱后获得的效应相似,即对低空间频率的反应优先降低。两种药物的效应时间进程有很大不同,对于高剂量的DFP,对所有空间频率的反应都大致均匀地受到抑制或消失。

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引用本文的文献

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Component-specific effects of physostigmine on the cat visual evoked potential.毒扁豆碱对猫视觉诱发电位的成分特异性影响。
Exp Brain Res. 1993;95(2):271-6. doi: 10.1007/BF00229785.
2
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Doc Ophthalmol. 1993;84(3):257-65. doi: 10.1007/BF01203658.