抗-M引起迟发性溶血性输血反应。
Anti-M causing delayed hemolytic transfusion reaction.
作者信息
Alperin J B, Riglin H, Branch D R, Gallagher M T, Petz L D
出版信息
Transfusion. 1983 Jul-Aug;23(4):322-4. doi: 10.1046/j.1537-2995.1983.23483276867.x.
Abstract
A 52-year-old gravida 1, para 1 woman with M- red cells experienced a delayed hemolytic transfusion reaction and exhibited an anti-M antibody following the infusion of four units of M+ red cells. Measurements of erythrocyte survival using 51Cr-labeled donor M+ and M- red cells and in vitro studies of monocyte-macrophage phagocytosis of sensitized reagent red cells implicate anti-M in the pathogenesis of hemolysis.
摘要
一名52岁、孕1产1、红细胞为M-型的女性，在输注4单位M+型红细胞后发生了迟发性溶血性输血反应，并出现了抗-M抗体。使用51Cr标记的供体M+型和M-型红细胞对红细胞存活率进行测定，以及对致敏试剂红细胞的单核巨噬细胞吞噬作用进行体外研究，结果表明抗-M在溶血发病机制中起作用。
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