Ismagulov A T, Nurgaliev K N
Zh Mikrobiol Epidemiol Immunobiol. 1983 May(5):84-7.
The reactogenicity, safety, immunogenicity and epidemiological effectiveness of inactivated virion vaccinal preparations from strains A (H3N2) Texas 1/77a, A (H1N1) and split adsorbed influenza chemical vaccine, as well as the character of local and systemic reactions to these vaccines were studied. The vaccinees showed a high percentage of seroconversions (42-69.4%) with antibody titers increasing 5 times and more. At the period of the epidemic outbreak of influenza in January 1980, caused by influenza virus A (H3N2) Texas 1/77a, morbidity rate among persons immunized with the vaccine homologous to the epidemic strain was 2.5 times lower than among nonimmunized persons.
对源自A（H3N2）德克萨斯1/77a株、A（H1N1）株的灭活病毒体疫苗制剂、裂解吸附流感化学疫苗的反应原性、安全性、免疫原性及流行病学有效性，以及这些疫苗的局部和全身反应特征进行了研究。疫苗接种者血清转化率较高（42 - 69.4%），抗体滴度增加了5倍及以上。在1980年1月由A（H3N2）德克萨斯1/77a流感病毒引起的流感流行爆发期间，接种与流行毒株同源疫苗的人群发病率比未接种人群低2.5倍。
