Thompson R
Behav Neural Biol. 1983 Jan;37(1):1-45. doi: 10.1016/s0163-1047(83)91047-6.
This paper focuses mainly on those findings derived from lesion studies on the rat which help to identify ensembles of neural structures concerned with the expression of previously learned responses. At the outset, the use of the lesion method in the search for those neurological circuits underlying memory is defended. This is followed by an evaluation of neocortical and subcortical systems in long-term memory. Subsequently, a modest list of tentative functional neural "complexes" involved in the maintenance of certain classes of learned responses is given, based largely upon the author's own research. It is concluded that the key to the understanding of the neurological substrates of long-term memory lies in the identification of those subcortical sites which interact with neocortical sites in the performance of complex learned tasks. The most likely subcortical sites involved in this interaction appear to inhabit the regions of the basal ganglia, limbic midbrain area, and ventral portions of the brainstem reticular formation.
本文主要关注那些源于对大鼠进行损伤研究的结果，这些结果有助于确定与先前习得反应的表达相关的神经结构集合。首先，对在寻找记忆背后的神经回路时使用损伤方法进行了辩护。接下来是对长期记忆中的新皮质和皮质下系统的评估。随后，在很大程度上基于作者自己的研究，给出了一份参与维持某些类别的习得反应的初步功能性神经“复合体”的简要清单。得出的结论是，理解长期记忆的神经基础的关键在于确定那些在执行复杂学习任务时与新皮质部位相互作用的皮质下部位。参与这种相互作用的最可能的皮质下部位似乎位于基底神经节、边缘中脑区域和脑干网状结构的腹侧部分。
