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[常压缺氧环境下饲养的白化大鼠脂质代谢的初步观察]

[Initial observations on lipid metabolism in the albino rat raised under normobaric hypoxic hypoxia].

作者信息

Quatrini U, Licciardi A

出版信息

Boll Soc Ital Biol Sper. 1983 Apr 30;59(4):549-52.

PMID:6882552
Abstract

The researches of Chiodi, Altland et Al. have shown fatty liver degeneration in hypoxic suckling rats. These alterations produced death within 30 days of life. In order to better understand the relationships between the fatty metabolism and hypoxia, we have studied total plasmatic lipids and cholesterol, glutamic-oxaloacetic and glutamic-pyruvic transaminase in the albino rats raised under normobaric hypoxia to avoid effects linked to barometric modifications. Total plasmatic lipids are reduced in hypoxic animals. In the others parameters we have not shown significant changes.

摘要

基奥迪、阿尔特兰等人的研究表明,缺氧的乳鼠会出现脂肪肝变性。这些变化会在出生后30天内导致死亡。为了更好地理解脂肪代谢与缺氧之间的关系,我们研究了在常压缺氧环境下饲养的白化大鼠的血浆总脂质、胆固醇、谷草转氨酶和谷丙转氨酶,以避免与气压变化相关的影响。缺氧动物的血浆总脂质减少。在其他参数方面,我们未发现显著变化。

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