[Ultrastructural analysis of changes in the lung parenchyma in the initial stages of experimental sepsis].

Histological and ultrastructural alterations in the lung parenchyma of rats with sepsis induced by implantation of 3 X 10(10) microorganisms (P. aeruginosa) beneath the skin were studied. Microorganisms with micropili were detected in septal spaces and in the alveoli 10 hours after implantation. Their effects were linked with microcirculatory alterations and destruction of endotheliocytes, alveolocytes and septal cells.