Hibbert J, Marks N J, Winter P J, Shaheen O H
Clin Otolaryngol Allied Sci. 1983 Jun;8(3):197-203. doi: 10.1111/j.1365-2273.1983.tb01427.x.
One hundred and three patients with an oral squamous carcinoma were studied in an attempt to determine the clinical factors which affect survival. The 5 yr actuarial survival of the whole group of patients was 55%. Although survival depended on clinical staging, in those patients with no palpable nodes on presentation the tumour size did not affect survival. The most significant factor determining survival was the presence of palpable lymph nodes on presentation. Palpable nodes were more likely in patients with large tumours than those with small tumours. On the basis of these findings a modification of the TNM classification is suggested giving more weight to the presence of cervical nodes than in the present staging system.
对103例口腔鳞状细胞癌患者进行了研究，以确定影响生存的临床因素。整个患者组的5年精算生存率为55%。虽然生存率取决于临床分期，但在就诊时未触及淋巴结的患者中，肿瘤大小并不影响生存。决定生存的最重要因素是就诊时可触及淋巴结。大肿瘤患者比小肿瘤患者更易出现可触及淋巴结。基于这些发现，建议对TNM分类进行修改，与目前的分期系统相比，给予颈部淋巴结的存在更多权重。
