Raucher H S, Eichenfield A H, Hodes H L
Clin Pediatr (Phila). 1983 Sep;22(9):601-4. doi: 10.1177/000992288302200901.
During 1981, we treated 20 infants, less than 24 months old, for nontyphoid Salmonella (NTSal) gastroenteritis (GE). Blood cultures were obtained in 17 cases, and Salmonella bacteremia was demonstrated in 8 (47%). Of the 13 children 3 to 24 months of age, 7 (54%) had positive blood cultures. One child (8 months old) appeared septic. The patients with bacteremia were treated with parenteral ampicillin. All 20 infants recovered, and no focal infectious complications occurred. The incidence of bacteremia in NTSal GE is highest in children under 2 years of age. Previous reports have shown that the peak incidence occurs among infants less than 3 months of age. An infant with Salmonella bacteremia may be afebrile and show no symptoms of sepsis. In most cases, bacteremia is transient and does not alter the course of NTSal GE, but it may result in life-threatening complications such as septicemia and meningitis. Therefore we believe an infant with NTSal GE under 3 months old should have a blood culture and receive antibiotic treatment.
1981年期间，我们对20名年龄小于24个月的婴儿进行了非伤寒沙门氏菌（NTSal）胃肠炎（GE）的治疗。17例进行了血培养，其中8例（47%）证实有沙门氏菌血症。在13名3至24个月大的儿童中，7例（54%）血培养呈阳性。1名儿童（8个月大）出现败血症症状。菌血症患者接受了肠胃外氨苄青霉素治疗。所有20名婴儿均康复，未发生局部感染并发症。NTSal GE菌血症的发生率在2岁以下儿童中最高。先前的报告显示，发病率高峰出现在3个月以下的婴儿中。患有沙门氏菌血症的婴儿可能不发热，也没有败血症症状。在大多数情况下，菌血症是短暂的，不会改变NTSal GE的病程，但可能导致危及生命的并发症，如败血症和脑膜炎。因此，我们认为3个月以下患有NTSal GE的婴儿应进行血培养并接受抗生素治疗。
