贫血对牛红细胞代谢的影响。

Effect of anaemia on red cell metabolism in cattle.

作者信息

Agar N S, Suzuki T, Roberts J, Evans J V

出版信息

Comp Biochem Physiol B. 1983;75(3):445-9. doi: 10.1016/0305-0491(83)90356-5.

Abstract

Six enzymes: glucose-6-phosphate dehydrogenase (G6PD), 6-phosphogluconate dehydrogenase (6PGD), glutathione reductase (GR), glutathione peroxidase (GSHPx), catalase and superoxide dismutase (SOD), and three metabolites: 2,3-diphosphoglycerate (DPG), adenosine triphosphate (ATP) and reduced glutathione (GSH), were measured in the red blood cells of cattle during experimental anaemia. There was a significant rise in the mean levels of DPG (from 0.85 to 1.69 mumol/gHb) and ATP (from 2.16 to 3.25 mumol/gHb) in the early phase of recovery. Enzyme activities also increased during the early recovery period.

摘要

在实验性贫血期间，对牛的红细胞中的六种酶：葡萄糖-6-磷酸脱氢酶（G6PD）、6-磷酸葡萄糖酸脱氢酶（6PGD）、谷胱甘肽还原酶（GR）、谷胱甘肽过氧化物酶（GSHPx）、过氧化氢酶和超氧化物歧化酶（SOD），以及三种代谢物：2,3-二磷酸甘油酸（DPG）、三磷酸腺苷（ATP）和还原型谷胱甘肽（GSH）进行了测量。在恢复早期，DPG的平均水平（从0.85微摩尔/克血红蛋白升至1.69微摩尔/克血红蛋白）和ATP的平均水平（从2.16微摩尔/克血红蛋白升至3.25微摩尔/克血红蛋白）显著升高。在恢复早期，酶活性也有所增加。