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[结直肠癌——与胆囊切除术或胆结石的关系?]

[Colorectal carcinoma--relation to cholecystectomy or to cholelithiasis?].

作者信息

Pinter D, Kratzsch K H, Waller H

出版信息

Dtsch Z Verdau Stoffwechselkr. 1983;43(3):130-6.

PMID:6884261
Abstract

On 2200 autopsy cases was investigated if patients after cholecystectomy or with cholelithiasis show a higher rate of colorectal cancer than those with normal gall bladder. Thereby was found that 7,6% of the cases with previously cholecystectomy and 7,0% of these with cholelithiasis had large bowel cancer, but only 2,9% of the dead without these findings. These differences were highly significant. In cases with state after gall bladder removing the significance was only given during the first four years post operation. Furthermore the connections were modified by age and sex. The results suggest that not a previously cholecystectomy seems to increase the danger of cancer in the colorectal area, but that the high risk factor could be connected with cholelithiasis.

摘要

对2200例尸检病例进行了调查,以研究胆囊切除术后患者或患有胆结石的患者患结直肠癌的几率是否高于胆囊正常的患者。结果发现,既往有胆囊切除术的病例中有7.6%患有大肠癌,有胆结石的病例中有7.0%患有大肠癌,而在没有这些情况的死者中,这一比例仅为2.9%。这些差异具有高度统计学意义。在胆囊切除术后的病例中,这种相关性仅在术后头四年存在。此外,这种关联还因年龄和性别而有所不同。结果表明,似乎不是既往的胆囊切除术增加了结直肠区域患癌的风险,而是高风险因素可能与胆结石有关。

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