• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

一种新型放射性药物:用于肾脏扫描的99mTc DMP

A new radiopharmaceutical: 99mTc DMP for renal scanning.

作者信息

Tanaka A, Machida T, Miki M, Shimada T

出版信息

Eur J Nucl Med. 1983;8(7):317-20. doi: 10.1007/BF00253759.

DOI:10.1007/BF00253759
PMID:6884382
Abstract

99mTc-Dimercaptopropionic acid (DMP), a new renal scanning agent was synthesized, and the optimum preparative conditions and stability of this compound were determined. It was demonstrated that scans performed with this agent in rats showed highly selective renal images which may be of promise in future clinical use. The relationships between chemical structure and renal affinity are discussed based on the present results.

摘要

合成了一种新型肾扫描剂99m锝-二巯基丙酸(DMP),并确定了该化合物的最佳制备条件和稳定性。结果表明,用该制剂对大鼠进行扫描可显示出高度选择性的肾脏图像,有望在未来临床应用中发挥作用。根据目前的结果讨论了化学结构与肾脏亲和力之间的关系。

相似文献

1
A new radiopharmaceutical: 99mTc DMP for renal scanning.一种新型放射性药物:用于肾脏扫描的99mTc DMP
Eur J Nucl Med. 1983;8(7):317-20. doi: 10.1007/BF00253759.
2
The influence of experimental conditions on the preparation of 99mTc-pyrrolidino-methyl tetracycline [99mTc-PMT] in the form of an instant kit.实验条件对即时试剂盒形式的99mTc-吡咯烷基甲基四环素[99mTc-PMT]制备的影响。
Nuklearmedizin. 1988 Aug;27(4):154-6.
3
Preparation, quality control and application of 99mTc-gluco-ene-diolate for renal scanning.用于肾脏扫描的99mTc-葡糖烯二醇酸盐的制备、质量控制及应用
Nuklearmedizin. 1985 Apr;24(2):93-5.
4
Chemical and biological studies of Tc-99m N,N'-bis(mercaptoacetamido)-ethylenediamine: a potential replacement for I-131 iodohippurate.锝-99m N,N'-双(巯基乙酰胺)乙二胺的化学与生物学研究:碘-131碘马尿酸盐的潜在替代品
J Nucl Med. 1981 Mar;22(3):258-63.
5
Optimal handling of dimercaptosuccinic acid for quantitative renal scanning.
J Nucl Med. 1980 Dec;21(12):1190-3.
6
Studies of chemical and biological properties of 99mTc-DMS (dimercaptosuccinic acid)--renal imaging agent.99mTc-DMS(二巯基丁二酸)——肾显像剂的化学与生物学性质研究。
Eur J Nucl Med. 1976 Dec 30;1(4):235-42. doi: 10.1007/BF00252169.
7
A kinetic model for 99mTc-DMSA in the rat.
Eur J Nucl Med. 1990;16(1):29-34. doi: 10.1007/BF01566009.
8
The influence of the method of preparation of the bone scanning agent 99mTc(Sn)EHDP on its tissue distribution in the rat.骨扫描剂99mTc(Sn)EHDP的制备方法对其在大鼠体内组织分布的影响。
Int J Appl Radiat Isot. 1982 Oct;33(10):917-28. doi: 10.1016/0020-708x(82)90137-5.
9
Technetium thiodiglycollic acid (99mTc-TDG). A new radiopharmaceutical with the potential for the assessment of renal function.硫代二乙醇酸锝(99mTc-TDG)。一种具有评估肾功能潜力的新型放射性药物。
Eur J Nucl Med. 1985;11(8):285-9. doi: 10.1007/BF00252338.
10
Renal gammagraphy with 99mTc-phosphomycin.用99mTc-磷霉素进行肾闪烁显像。
Eur J Nucl Med. 1985;10(3-4):134-7. doi: 10.1007/BF00252721.

引用本文的文献

1
First evaluation of technetium-99m dimercaptopropionyl albumin as a possible tracer agent for ventriculography in a volunteer.在一名志愿者身上首次评估锝-99m二巯基丙酰白蛋白作为脑室造影可能的示踪剂。
Eur J Nucl Med. 1994 Sep;21(9):906-12. doi: 10.1007/BF00238113.

本文引用的文献

1
Complexes of technetium with hydroxycarboxylic acids: gluconic, glucoheptonic, tartaric, and citric.锝与羟基羧酸形成的配合物:葡萄糖酸、葡庚糖酸、酒石酸和柠檬酸。
J Nucl Med. 1980 Nov;21(11):1086-90.
2
Optimal handling of dimercaptosuccinic acid for quantitative renal scanning.
J Nucl Med. 1980 Dec;21(12):1190-3.
3
Comparison of 99mTc complexes for renal imaging.用于肾脏显像的99mTc配合物的比较。
J Nucl Med. 1975 May;16(5):357-67.
4
99mTechnetium-unithiol complex, a new pharmaceutical for kidney scintigraphy.99m锝-二巯基丁二酸钠复合物,一种用于肾脏闪烁扫描的新型药物。
Nuklearmedizin. 1976 Dec;15(6):282-6.
5
The reaction of stannous ion with thiomalic acid in the preparation of 99mTc--thiomalate as a radiopharmaceutical.在制备作为放射性药物的99mTc-硫代苹果酸盐过程中亚锡离子与硫代苹果酸的反应。
Int J Appl Radiat Isot. 1977 Apr;28(4):387-93. doi: 10.1016/0020-708x(77)90131-4.
6
Basic studies of various 99mTc-labelled renal agents and clinical application of 99mTc-malate.各种99mTc标记的肾显像剂的基础研究及99mTc-苹果酸盐的临床应用。
Nuklearmedizin. 1977 Feb;16(1):36-41.
7
Preparation of various Tc-99m dimercaptosuccinate complexes and their evaluation as radiotracers.各种锝-99m二巯基丁二酸配合物的制备及其作为放射性示踪剂的评估。
J Nucl Med. 1977 Dec;18(12):1222-9.
8
Localization of low molecular weight 99mTc-labeled dimercaptodicarboxylic acids in kidney tissue.低分子量99mTc标记的二巯基二羧酸在肾组织中的定位
J Pharm Sci. 1979 May;68(5):621-3. doi: 10.1002/jps.2600680528.