Nouwen E J, Decuypere E, Michels H, Kühn E R
Gen Comp Endocrinol. 1983 Jun;50(3):445-51. doi: 10.1016/0016-6480(83)90265-4.
Decreasing hematocrit values were observed in chick embryos, from Day 17 to 1 day posthatching. Arginine vasotocin (AVT) and mesotocin (MT) were determined radioimmunologically in serum, neural lobe, and hypothalamic tissue. Serum levels of AVT and MT were significantly increased on Day 18 of incubation compared to Day 17. Thereafter AVT levels decreased, reaching at hatching levels even below Day 17. Serum MT remained elevated on Day 19, but decreased thereafter to the concentration values of Day 17. The amount of AVT in the preoptic hypothalamus and infundibulum was maximal on Day 19, whereas in the neural lobe the maximum was attained on Day 20. The MT content of the infundibulum and neural lobe reached a maximum plateau on Day 18. These results suggest that a stimulation of the hypothalamo-neurohypophyseal axis in the chick embryo occurs at the end of incubation. A possible causal relation with the observed decreasing hematocrit values is discussed.
在鸡胚中观察到，从孵化第17天到出壳后1天，血细胞比容值逐渐降低。采用放射免疫法测定了血清、神经叶和下丘脑组织中的精氨酸血管催产素（AVT）和中催产素（MT）。与第17天相比，孵化第18天血清中AVT和MT水平显著升高。此后，AVT水平下降，到出壳时甚至低于第17天的水平。血清MT在第19天仍保持升高，但此后降至第17天的浓度值。视前下丘脑和漏斗部中AVT的含量在第19天达到最大值，而神经叶中的最大值在第20天达到。漏斗部和神经叶中MT的含量在第18天达到最大平台期。这些结果表明，在孵化末期鸡胚的下丘脑-神经垂体轴受到刺激。本文讨论了其与观察到的血细胞比容值下降之间可能的因果关系。
