White C L, Hamilton S R, Diamond M P, Cameron J L
Gut. 1983 Sep;24(9):857-62. doi: 10.1136/gut.24.9.857.
A well documented case of a patient with both Crohn's disease and ulcerative colitis is presented. A 29 year old woman underwent resection of her terminal ileum and ascending colon for typical Crohn's disease with ileocolitis. Eleven years later, an ileoproctocolectomy was performed for typical ulcerative colitis involving the left colon. The resection specimen also showed evidence of colonic Crohn's disease near the anastomotic site. This unusual case shows that Crohn's disease and ulcerative colitis can occur in the same patient. The rarity of such cases supports the concept that Crohn's disease and ulcerative colitis are separate entities, rather than different manifestations of the same disease process.
本文介绍了一例记录详实的同时患有克罗恩病和溃疡性结肠炎的患者。一名29岁女性因典型的克罗恩病伴回结肠炎接受了末端回肠和升结肠切除术。11年后,因累及左半结肠的典型溃疡性结肠炎接受了回肠直肠结肠切除术。切除标本在吻合口附近也显示出结肠克罗恩病的迹象。这一罕见病例表明,克罗恩病和溃疡性结肠炎可发生于同一患者。此类病例的罕见性支持了克罗恩病和溃疡性结肠炎是独立疾病实体,而非同一疾病过程的不同表现这一观点。