Cook M G
Gut. 1972 Dec;13(12):970-2. doi: 10.1136/gut.13.12.970.
The size of the related lymph nodes and their histology has been correlated in 34 specimens of Crohn's disease. Granulomata were shown not to affect the maximum diameter of the lymph nodes nor to be more frequent in large nodes. The enlargement of lymph nodes appeared to be due to simple, non-specific, reactive changes. Granulomatous lymph nodes were found in 38% of all our cases of Crohn's disease and in 63% of those cases with granulomata in the bowel wall. One case was found with granulomata in the lymph nodes which were not seen in the bowel wall. The mesenteric lymph nodes of 22 cases of ulcerative colitis were shown to be not significantly different in size from those of Crohn's disease. The diameter of the lymph nodes on the histological section was shown to underestimate the diameter of nodes in the fresh state by a factor of 1.5.
在34例克罗恩病标本中，对相关淋巴结的大小及其组织学特征进行了相关性研究。结果显示，肉芽肿并不影响淋巴结的最大直径，在大的淋巴结中也并非更常见。淋巴结肿大似乎是由单纯的、非特异性的反应性变化引起的。在我们所有的克罗恩病病例中，38%发现有肉芽肿性淋巴结，在肠壁有肉芽肿的病例中，这一比例为63%。有1例在肠壁未见肉芽肿的情况下，在淋巴结中发现了肉芽肿。22例溃疡性结肠炎患者的肠系膜淋巴结大小与克罗恩病患者相比无显著差异。组织学切片上淋巴结的直径显示比新鲜状态下淋巴结的直径低估了1.5倍。
