Miletić V D, Lukić G, Radojicic C, Dujic A
Immunol Lett. 1983 May;6(5):271-6. doi: 10.1016/0165-2478(83)90017-2.
Antibody content against rabbit red blood cells (anti-RaRBC) in murine sera of different strains (Swiss, CBA, C57BL/6, AKR, BALB/c) and activity of complement alternative pathway (AP) were investigated. In contrast to the CBA and C57BL/6, random-bred Swiss strain and inbred BALB/c and AKR strains are good producers of these natural antibodies. There is no correlation between AP activity and anti-RaRBC content. Isolated human anti-RaRBC antibodies, IgM and IgG classes, lead to the enhancement of APhu and APmo activity, contrary to the murine anti-RaRBC which belong solely to IgM class, and do not express this capability.
研究了不同品系（瑞士小鼠、CBA、C57BL/6、AKR、BALB/c）小鼠血清中抗兔红细胞抗体（抗-RaRBC）的含量以及补体替代途径（AP）的活性。与CBA和C57BL/6不同，随机繁殖的瑞士小鼠品系以及近交系BALB/c和AKR品系是这些天然抗体的良好产生者。AP活性与抗-RaRBC含量之间无相关性。分离出的人抗-RaRBC抗体，IgM和IgG类，可导致人AP和小鼠AP活性增强，这与仅属于IgM类且不具有此能力的小鼠抗-RaRBC相反。
