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基于氨和尿素排泄对六指蛙诱导的短暂高氨血症的研究

Induced transient hyperammonemia in Rana hexadactyla with reference to the ammonia and urea excretion.

作者信息

Neeraja P, Swami K S

出版信息

Indian J Physiol Pharmacol. 1983 Apr-Jun;27(2):123-8.

PMID:6885124
Abstract

Different ammonia toxicity induced by ammonium acetate administration in frogs lead to variable excretion of ammonia and urea into the medium. When 11.45 mM/kg body weight of ammonium acetate was administered, ammonia excretion increased while urea excretion decreased. When 4.17 mM/kg body weight of ammonium acetate is administered, the urea excretion increased while ammonia excretion decreased. The possible metabolic conversion of ammonia and urea by the animal at high and low ammonium acetate administration has been discussed.

摘要

给青蛙注射醋酸铵所诱导的不同氨毒性会导致氨和尿素向培养基中的排泄量发生变化。当以11.45 mM/kg体重的剂量注射醋酸铵时,氨的排泄量增加而尿素的排泄量减少。当以4.17 mM/kg体重的剂量注射醋酸铵时,尿素的排泄量增加而氨的排泄量减少。文中讨论了在高剂量和低剂量醋酸铵给药情况下,动物体内氨和尿素可能的代谢转化情况。

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