Matus R E, Leifer C E, Gordon B R, MacEwen E G, Hurvitz A I
J Am Vet Med Assoc. 1983 Jul 15;183(2):215-8.
Hyperviscosity syndrome associated with IgA monoclonal gammopathy was diagnosed in 3 dogs. Continuous plasmapheresis and alkylation therapy with melphalan and cyclophosphamide induced sustained remission in each dog. There was resolution of clinical signs associated with hyperviscosity syndrome and rapid establishment of normal serum protein concentrations.
3只犬被诊断为与IgA单克隆丙种球蛋白病相关的高黏滞血症综合征。连续进行血浆置换以及使用美法仑和环磷酰胺进行烷基化治疗，使每只犬都实现了持续缓解。与高黏滞血症综合征相关的临床症状得到缓解，血清蛋白浓度迅速恢复正常。
