Patterns of silver staining of human chromosomes.

The chromosomes of twenty individuals with normal karyotypes were studied to determine the patterns of staining with the Ag--AS technique. These patterns were shown to be variable from one individual to another, but characteristic and constant within each individual. In addition, one patient with chronic lymphocytic leukemia was studied, and shown to have an Ag--AS staining pattern that was distinctly different from that of normal subjects.