Glass R I, Stoll B J, Huq M I, Struelens M J, Blaser M, Kibriya A K
J Infect Dis. 1983 Aug;148(2):292-6. doi: 10.1093/infdis/148.2.292.
Epidemiologic and clinical features of infection with Campylobacter jejuni in Bangladesh were examined in (1) diarrheal patients infected with C jejuni, (2) healthy control subjects, and (3) village children who were cultured monthly and at each diarrheal episode during a 10-month period. C jejuni was isolated from 437 (14%) of 3,038 outpatients with diarrhea. These patients had no distinct clinical presentation and were more likely to have a mixed infection than were patients infected with other pathogens (59% vs 42%, P less than 0.01). Age-specific infection rates were greatest in infants and did not differ significantly from those in control subjects. C jejuni was isolated less frequently from village children with diarrhea than from those cultured routinely (5% vs 9%, P less than 0.05). Forty percent of 47 patients with C jejuni vs 23% of 48 control subjects (P less than 0.01) had an elevated convalescent-phase antibody titer as determined by complement fixation test. In Bangladesh, enteric infection with C jejuni is common but often asymptomatic, although pathogenicity is suggested by serologic response in some patients.
在孟加拉国，对空肠弯曲菌感染的流行病学和临床特征进行了研究，研究对象包括：（1）感染空肠弯曲菌的腹泻患者；（2）健康对照者；（3）在10个月期间每月以及每次腹泻发作时进行培养的乡村儿童。在3038例腹泻门诊患者中，有437例（14%）分离出空肠弯曲菌。这些患者没有明显的临床表现，与感染其他病原体的患者相比，更易发生混合感染（59%对42%，P<0.01）。特定年龄的感染率在婴儿中最高，与对照者相比无显著差异。腹泻乡村儿童中空肠弯曲菌的分离率低于常规培养的儿童（5%对9%，P<0.05）。通过补体结合试验测定，47例空肠弯曲菌感染患者中有40%恢复期抗体效价升高，而48例对照者中这一比例为23%（P<0.01）。在孟加拉国，空肠弯曲菌肠道感染很常见，但通常无症状，不过一些患者的血清学反应提示其具有致病性。
