Landy P J
J Neurol Neurosurg Psychiatry. 1983 Jul;46(7):659-61. doi: 10.1136/jnnp.46.7.659.
110 cases of optic neuritis were prospectively studied. 62 (56%) developed multiple sclerosis, 13 were lost to survey. However, eight of these had recurrent episodes of optic neuritis. If recurrent episodes of optic neuritis are accorded the same significance as demyelination elsewhere in the CNS, then the incidence of multiple sclerosis in the series rose to 71%, similar to that predicted on an actuarial basis.
对110例视神经炎患者进行了前瞻性研究。其中62例(56%)发展为多发性硬化症,13例失访。然而,这些失访患者中有8例出现了复发性视神经炎。如果将复发性视神经炎与中枢神经系统其他部位的脱髓鞘病变视为具有同等重要性,那么该系列研究中多发性硬化症的发病率升至71%,与基于精算预测的发病率相似。