Hyland R H, Gordon D A, Broder I, Davies G M, Russell M L, Hutcheon M A, Reid G D, Cox D W, Corey P N, Mintz S
J Rheumatol. 1983 Jun;10(3):395-405.
We have conducted a prospective comparison of 155 rheumatoid patients and 95 control subjects. Both groups were selected without regard to respiratory status, but were comparable in age, sex and smoking experience. The prevalence of respiratory symptoms, of past respiratory illnesses and of pulmonary function findings of airway obstruction was similar in both groups. However, the rheumatoids showed an increased frequency of chest crackles and abnormal chest radiographs, and had pulmonary function changes suggestive of a restrictive ventilatory defect. These pulmonary abnormalities were associated with smoking, the presence of nonpulmonary extraarticular features, the level of rheumatoid disease activity and treatment with oral corticosteroid or gold.
我们对155例类风湿患者和95例对照者进行了前瞻性比较。两组的选择均未考虑呼吸状况，但在年龄、性别和吸烟经历方面具有可比性。两组在呼吸道症状、既往呼吸道疾病的患病率以及气道阻塞的肺功能检查结果方面相似。然而，类风湿患者出现胸部啰音和胸部X线片异常的频率增加，并且存在提示限制性通气功能障碍的肺功能改变。这些肺部异常与吸烟、非肺部关节外表现的存在、类风湿疾病活动水平以及口服皮质类固醇或金制剂治疗有关。
