Ruckebusch Y, Ooms L
J Vet Pharmacol Ther. 1983 Jun;6(2):127-31. doi: 10.1111/j.1365-2885.1983.tb00389.x.
The effects of intravenous administration of 5-HT on the patterns of reticulo-rumen contractions were studied in conscious sheep. Contractions were measured by strain gauges applied to the external wall of the reticulum and the ventral and/or dorsal sac of the rumen. The responses to 5-HT comprised (i) a short-lived contraction followed by (ii) a sustained increase in muscle tone and (iii) a concomitant inhibition of the extrinsic reticulo-rumen contractions. The corresponding blockades produced by (i) atropine, (ii) 5-HT antagonists and (iii) chemical sympathectomy suggest involvement of a peripheral cholinergic mechanism in the initial contractile response and a central adrenergic mechanism in the reflex inhibition of extrinsic reticulo-rumen contractions.
在清醒绵羊中研究了静脉注射5-羟色胺（5-HT）对网瘤胃收缩模式的影响。通过将应变仪应用于网胃外壁以及瘤胃腹囊和/或背囊来测量收缩。对5-HT的反应包括：（i）短暂的收缩，随后是（ii）肌张力持续增加，以及（iii）同时抑制外在性网瘤胃收缩。由（i）阿托品、（ii）5-HT拮抗剂和（iii）化学交感神经切除术产生的相应阻断作用表明，外周胆碱能机制参与了最初的收缩反应，而中枢肾上腺素能机制参与了对外在性网瘤胃收缩的反射性抑制。
