Flint A P, Burton R D, Gadsby J E, Heap R B, Sheldrick E L
J Steroid Biochem. 1983 Jul;19(1C):973-8. doi: 10.1016/0022-4731(83)90042-0.
In both pigs and sheep in early pregnancy the function of the corpora lutea is maintained beyond the normal time of luteal regression. The mechanism by which this is brought about appears in both species to involve reduced uterine secretion of the uterine luteolysin, prostaglandin F2 alpha, as a result of the secretion of an embryonic antiluteolysin. In the pig this antiluteolysin is an oestrogen, and in the sheep, the protein trophoblastin. Loss of luteal oxytocin also occurs in sheep early in pregnancy, and this may contribute to reduced luteolytic drive during the period between 25 and 50 days of gestation when the embryonic antiluteolysin is absent. Concentrations of oxytocin in the corpora lutea appear to be controlled by a factor of uterine origin, since luteal oxytocin is also depleted after hysterectomy.
在妊娠早期的猪和羊中，黄体的功能在正常黄体退化时间之后仍得以维持。在这两个物种中，导致这种情况发生的机制似乎都涉及到由于胚胎抗溶黄体素的分泌，子宫溶黄体素前列腺素F2α的分泌减少。在猪中，这种抗溶黄体素是一种雌激素，而在羊中，则是蛋白质滋养层蛋白。在妊娠早期的羊中，黄体催产素也会减少，这可能有助于在妊娠25至50天期间，当胚胎抗溶黄体素不存在时，降低溶黄体作用。黄体中的催产素浓度似乎受子宫来源的一种因子控制，因为子宫切除术后黄体催产素也会减少。
