Fatranská M, Vargová M, Rosival L, Bátora V, Németh S, Janeková D
Chronobiologia. 1978 Jan-Mar;5(1):39-44.
LD50 values after i.p. doses of phenitrotion (PH), dichlorvos (D) and methyl parathion (MP) were established at 0600, 1200, 1800 and 0000 and plasma corticosterone was determined in male rats. The PH toxicity was significantly higher at 0600 than at 1800. Moreover, there was a significant difference between the PH toxicity at 1200 (lower) and 0000 (higher). The D toxicity differed significantly only between 1200 (higher). There was however a lack of circadian susceptibility, rhythm to MP. The results differ according to the metabolic fate and the solubility of the tested compounds.
腹腔注射硝硫磷（PH）、敌敌畏（D）和甲基对硫磷（MP）后，于06:00、12:00、18:00和00:00测定雄性大鼠的半数致死剂量（LD50），并测定血浆皮质酮。PH的毒性在06:00时显著高于18:00时。此外，PH在12:00（较低）和00:00（较高）时的毒性存在显著差异。D的毒性仅在12:00（较高）时存在显著差异。然而，MP缺乏昼夜敏感性节律。结果因受试化合物的代谢命运和溶解度而异。
