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猴子局灶性运动性癫痫发作时基底神经节癫痫活动传播的地形分布。

Topographical distribution of propagation of seizure activity in the basal ganglia during focal motor seizures in the monkey.

作者信息

Hosokawa S, Kato M, Kuroiwa Y

出版信息

Neurosci Lett. 1983 Jul 15;38(1):29-33. doi: 10.1016/0304-3940(83)90105-2.

DOI:10.1016/0304-3940(83)90105-2
PMID:6888804
Abstract

Topographical distribution of the propagation of seizure activity in the basal ganglia was studied during focal motor seizures from the focus in the face-hand area of Area 4 in the monkey, using the [14C]deoxyglucose autoradiography method. The focal seizures were induced by injecting potassium penicillin G into the face-hand area in the right motor cortex. The propagation of seizure activity in the basal ganglia was localized in the ventral and caudal parts of the ipsilateral putamen and globus pallidus lateral and medial segments, and in part of the reticular portion of substantia nigra. These areas in the basal ganglia seem to be functionally linked to the face-hand area of the motor cortex.

摘要

利用[14C]脱氧葡萄糖放射自显影法,研究了猴子大脑4区面手区域病灶引发的局灶性运动性癫痫发作期间,癫痫活动在基底神经节中的传播的地形分布。通过向右侧运动皮层的面手区域注射青霉素G钾来诱发局灶性癫痫发作。癫痫活动在基底神经节中的传播定位于同侧壳核以及苍白球外侧和内侧段的腹侧和尾侧部分,以及黑质网状部的一部分。基底神经节中的这些区域似乎在功能上与运动皮层的面手区域相关联。

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Topographical distribution of propagation of seizure activity in the basal ganglia during focal motor seizures in the monkey.猴子局灶性运动性癫痫发作时基底神经节癫痫活动传播的地形分布。
Neurosci Lett. 1983 Jul 15;38(1):29-33. doi: 10.1016/0304-3940(83)90105-2.
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引用本文的文献

1
The role of the basal ganglia in the control of seizure.基底神经节在癫痫控制中的作用。
J Neural Transm (Vienna). 2018 Mar;125(3):531-545. doi: 10.1007/s00702-017-1768-x. Epub 2017 Aug 1.
2
Paradoxical anticonvulsant activity of the excitatory amino acid N-methyl-D-aspartate in the rat caudate-putamen.兴奋性氨基酸N-甲基-D-天冬氨酸在大鼠尾状核-壳核中的反常抗惊厥活性
Proc Natl Acad Sci U S A. 1987 Mar;84(6):1689-93. doi: 10.1073/pnas.84.6.1689.
3
Regional changes in the concentrations of glutamate, glycine, taurine, and GABA in the vitamin B-6 deficient developing rat brain: association with neonatal seizures.
维生素B-6缺乏的发育中大鼠脑内谷氨酸、甘氨酸、牛磺酸和γ-氨基丁酸浓度的区域变化:与新生儿惊厥的关联
Neurochem Res. 1989 Sep;14(9):889-97. doi: 10.1007/BF00964820.