Caveness W F, Kato M, Malamut B L, Hosokawa S, Wakisaka S, O'Neill R R
Ann Neurol. 1980 Mar;7(3):213-21, 232-5. doi: 10.1002/ana.410070304.
The rate of local cerebral glucose utilization was determined for quantification of energy metabolism in macrostructures of the sensorimotor system during propagation of focal motor seizures in 24-month-old monkeys. The rate was measured in 4 control animals and in 4 monkeys each with seizures limited to the contralateral face, seizures of the contralateral face and upper extremity, and bilateral expression of seizures. Glucose utilization increased significantly, primarily unilaterally, with propagation. The increase was greatest in the sensory and motor cerebral cortices, putamen, and globus pallidus, was somewhat less in sensory and motor thalamic relay nuclei, and was least in the cerebellar cortex.
在24个月大的猴子局灶性运动性癫痫发作传播期间，测定局部脑葡萄糖利用率以量化感觉运动系统宏观结构中的能量代谢。对4只对照动物以及4只分别出现对侧面部癫痫发作、对侧面部和上肢癫痫发作以及双侧癫痫发作的猴子进行了该速率的测量。随着癫痫发作传播，葡萄糖利用率显著增加，主要为单侧增加。在感觉和运动脑皮质、壳核和苍白球中增加最大，在感觉和运动丘脑中继核中增加稍少，而在小脑皮质中增加最少。
