Fellenberg A J, Phillipou G, Seamark R F
Clin Endocrinol (Oxf). 1982 Jul 1;17(1):71-5. doi: 10.1111/j.1365-2265.1982.tb02635.x.
The excretion of 6-sulphatoxy melatonin in urine has been shown to provide a reliable index of melatonin production in man. Daily measurements made in two healthy ovulating women showed that both the total amount excreted/day and the proportion excreted during the sleep period remained relatively constant for each subject throughout the menstrual cycle. These data do not support the view that there are changes in melatonin production which correlate with cyclical reproductive endocrine function in the human.
尿中6-硫酸氧褪黑素的排泄已被证明可提供人体褪黑素生成的可靠指标。对两名健康的排卵女性进行的每日测量显示，在整个月经周期中，每位受试者每天排泄的总量以及睡眠期间排泄的比例都保持相对恒定。这些数据并不支持这样的观点，即人类褪黑素生成的变化与周期性生殖内分泌功能相关。
