Murialdo G, Fonzi S, Costelli P, Solinas G P, Parodi C, Marabini S, Fanciullacci M, Polleri A
Department of Endocrinological and Metabolic Sciences, University of Genoa, Italy.
Cephalalgia. 1994 Jun;14(3):205-9. doi: 10.1046/j.1468-2982.1994.014003205.x.
Nocturnal urinary melatonin excretion was significantly decreased throughout an ovarian cycle in 12 migraine without aura patients compared to 8 healthy controls. Normal increases in urinary melatonin excretion during the luteal phase was less pronounced in the migraine patients. Melatonin excretion was further decreased during headache. The data indicate impaired pineal function in migraine.
与8名健康对照者相比，12名无先兆偏头痛患者在整个卵巢周期中夜间尿褪黑素排泄量显著降低。偏头痛患者在黄体期尿褪黑素排泄量的正常增加不太明显。在头痛期间，褪黑素排泄量进一步降低。这些数据表明偏头痛患者松果体功能受损。
