Antman K H, Corson J, Greenberger J, Wilson R
Cancer. 1982 Nov 15;50(10):2000-3. doi: 10.1002/1097-0142(19821115)50:10<2000::aid-cncr2820501004>3.0.co;2-u.
Five patients with angiosarcoma of the breast were treated with surgery, radiotherapy and an adjuvant Adriamycin containing regimen. Two patients remain disease-free at 38+ and 20+ months. The median survival of previously reported cases is 22 months with only five patients disease-free at five years. Possible hormonal influences in the etiologic cause of angiosarcoma of the breast are discussed and the importance of early diagnosis and treatment in these relatively young patients is emphasized.
5例乳腺血管肉瘤患者接受了手术、放疗及含阿霉素的辅助化疗方案治疗。2例患者分别在38多个月和20多个月时仍无疾病复发。既往报道病例的中位生存期为22个月,仅有5例患者在5年后无疾病复发。文中讨论了乳腺血管肉瘤病因中可能存在的激素影响因素,并强调了对这些相对年轻患者进行早期诊断和治疗的重要性。