Freund H, Gendry P
Eur J Appl Physiol Occup Physiol. 1978 Aug 15;39(2):123-35. doi: 10.1007/BF00421717.
Arterial blood lactate was measured at 10 s time intervals after a 3 min strenuous exercise for six athletes pedaling a bicycle ergometer in the sitting position. Recovery curves were fitted to the equation: Y(t) = A1(1-e-gamma1t)+A2(1-e-gamma2t)(0). The evolution of arterial lactate concentrations during recovery can accurately be represented by this equation. The values of the coefficients A and gamma found were used for a numerical application to an open two-compartment model: the "working muscle space" (1) and the "lactate space" (2). Intramuscular concentrations, the transfer coefficients from compartment 1 to compartment 2 and from compartment 2 to compartment 1 and the fractional turnover and basal turnover rate were calculated. Computed intramuscular lactate concentrations at the end of exercise compare favorably with those found earlier by muscular biopsic samplings. The turnover data are higher than those previously reported. This discrepancy may possibly be attributed to the method of mathematical analysis.
对六名运动员在坐姿下蹬自行车测力计进行3分钟剧烈运动后，每隔10秒测量一次动脉血乳酸。恢复曲线拟合方程为：Y(t)=A1(1 - e^(-γ1t))+A2(1 - e^(-γ2t))(0)。恢复过程中动脉乳酸浓度的变化可以用该方程准确表示。所得到的系数A和γ值被用于一个开放双室模型的数值应用：“工作肌肉空间”(1)和“乳酸空间”(2)。计算了肌肉内浓度、从隔室1到隔室2以及从隔室2到隔室1的转移系数，以及分数周转率和基础周转率。运动结束时计算出的肌肉内乳酸浓度与早期通过肌肉活检采样得到的结果相当。周转率数据高于先前报道的数据。这种差异可能归因于数学分析方法。
