Ulven A, Svanes K, Raugstad T S
Eur Surg Res. 1978;10(4):266-71. doi: 10.1159/000128016.
Standardized ulcers were produced in rats by local application of acetic acid to the serosal surface of the stomach. Ulcers induced at the lesser curvature, the greater curvature or the posterior wall were found to be of similar size after 2 and 4 weeks. In a group of animals the greater omentum was excised just before the application of acid. Omentectomized animals and control animals were examined 24 h, 1, 3 and 6 weeks after ulcer induction. In omentectomized animals, the ulcers were usually healed or very small after 3 and 6 weeks, while in the control animals most of the ulcers were still large. It is concluded that omentectomy leads to a marked acceleration in the healing of gastric ulcers in rats.
通过将乙酸局部应用于大鼠胃浆膜表面来制造标准化溃疡。在胃小弯、大弯或后壁诱导产生的溃疡在2周和4周后被发现大小相似。在一组动物中，在施加酸之前切除大网膜。在溃疡诱导后24小时、1周、3周和6周对切除大网膜的动物和对照动物进行检查。在切除大网膜的动物中，溃疡在3周和6周后通常愈合或非常小，而在对照动物中，大多数溃疡仍然很大。得出的结论是，切除大网膜可导致大鼠胃溃疡愈合明显加速。
