Watanabe T, Torii Y, Ochiai M, Kuribayashi T, Kitamura M, Kohno Y, Furukawa K, Matsukubo H, Katsume H, Ijichi H
J Cardiogr. 1982 Sep;12(3):625-34.
The thickness and motion of the right ventricular wall (RVW) were studied with two-dimensional echocardiography from a subxiphoid approach in 20 normal subjects (N Group), 86 patients with hypertension (HT Group) and 20 patients with hypertrophic cardiomyopathy (HCM Group). Comparison was made between the patients with and without echocardiographic RVW hypertrophy in each patient group in regard to the thickness of the interventricular septum (IVS) and the left ventricular posterior wall (LVPW) as well as the motion of the RVW and cardiac catheterization data. 1. RVW hypertrophy was visualized in 39.5% of the HT Group and in 40% of the HCM Group. There was no difference in the thickness of RVW between the two groups. 2. A localized hypertrophy and an abnormal motion of RVW were obtained in the HCM Group, but not in the HT Group. 3. RVW hypertrophy in the HT Group was seen in patients with marked IVS hypertrophy, while that in the HCM Group was not related to IVS hypertrophy. 4. Pulmonary arterial pressure remained normal in each group. Therefore, RVW hypertrophy did not appear to be the result of pressure overload. 5. Right atrial mean pressure and right ventricular end-diastolic pressure were elevated only in HCM patients with RVW hypertrophy. We conclude that there is a different mechanism in the mode of production of RVW hypertrophy between patients with hypertension and those with hypertrophic cardiomyopathy.
采用剑突下二维超声心动图对20名正常受试者（N组）、86例高血压患者（HT组）和20例肥厚型心肌病患者（HCM组）的右心室壁（RVW）厚度及运动情况进行研究。比较各患者组中有无超声心动图显示RVW肥厚的患者在室间隔（IVS）和左心室后壁（LVPW）厚度、RVW运动以及心导管检查数据方面的差异。1. HT组中39.5%的患者及HCM组中40%的患者可见RVW肥厚。两组之间RVW厚度无差异。2. HCM组出现RVW局限性肥厚及运动异常，而HT组未出现。3. HT组中RVW肥厚见于IVS明显肥厚的患者，而HCM组中RVW肥厚与IVS肥厚无关。4. 每组患者的肺动脉压均保持正常。因此，RVW肥厚似乎并非压力负荷过重的结果。5. 仅在伴有RVW肥厚的HCM患者中右心房平均压及右心室舒张末期压力升高。我们得出结论，高血压患者与肥厚型心肌病患者RVW肥厚的产生机制不同。
