Burnett D, Bradwell A R
Biol Neonate. 1980;37(5-6):302-7. doi: 10.1159/000241291.
12 proteins were studied in serum and amniotic fluid from 20 women in late pregnancy by two-dimensional immunoelectrophoresis. A close inverse relationship was observed between the amniotic fluid/serum concentration ratios of 11 proteins and their Stokes radii. These proteins enter the liquor from the maternal blood by molecular filtration. The concentration of alpha 1-antichymotrypsin in amniotic fluid was often higher than expected and the protein was often partially complexed. alpha 1-Antichymotrypsin is probably not actively secreted into amniotic fluid but may be selectively retained after complexing.
通过二维免疫电泳对20名妊娠晚期女性的血清和羊水进行了12种蛋白质的研究。观察到11种蛋白质的羊水/血清浓度比与其斯托克斯半径之间存在密切的负相关关系。这些蛋白质通过分子过滤从母体血液进入羊水。羊水中α1 -抗糜蛋白酶的浓度常常高于预期，且该蛋白质常部分形成复合物。α1 -抗糜蛋白酶可能并非主动分泌到羊水中，而是在形成复合物后可能被选择性保留。
