Kowe R, Schroter R C, Matthews F L, Hitchings D
J Biomech. 1986;19(7):541-9. doi: 10.1016/0021-9290(86)90127-2.
Displacement method finite element theory is used to examine the structural and elastic properties of the constituent network of elastin and collagen of the alveoli that form the mammalian lung. The role of the surface tension of pulmonary surfactant of the lung is also examined using an area-dependent relationship inferred from experimental studies. The pressure-volume (PV) curves of the resulting model are found to compare favourably with measured pressure-volume curves for whole lungs filled with air (surface tension included) and saline (no surface tension effects).
采用位移法有限元理论来研究构成哺乳动物肺的肺泡中弹性蛋白和胶原蛋白组成网络的结构和弹性特性。还利用从实验研究推断出的面积相关关系来研究肺表面活性物质的表面张力作用。结果发现,所得模型的压力-容积(PV)曲线与充满空气(包括表面张力)和盐水(无表面张力影响)的全肺实测压力-容积曲线相比具有优势。