Ho K C, Roessmann U, Straumfjord J V, Monroe G
Arch Pathol Lab Med. 1980 Dec;104(12):635-9.
The weights of fresh brains obtained at consecutive autopsies over a period of five years were reviewed. Brains with lesions, such as large tumor, hemorrhage, infarct, or edema, were excluded. Analysis of the brain weight of 1,261 subjects, aged 25 to 80 years, show that the mean brain weight decreases in order from white men to black men to white women to black women. These differences are statistically significant and become apparent at age 6 years. The rate of decrease for the brain weight after age 25 years is highest for white men, followed by black women, white women, and black men, and, except that between white men and white women, the differences are statistically insignificant. Contrary to earlier reports, the mass decreases rapidly after age 80 years. In evaluating an individual brain weight, it is important to compare it with the norm for each subgroup of a given age.
回顾了在五年期间连续尸检所获得的新鲜大脑的重量。排除了有病变的大脑，如大肿瘤、出血、梗死或水肿。对1261名年龄在25至80岁之间的受试者的脑重分析表明，平均脑重从白人男性到黑人男性再到白人女性最后到黑人女性依次递减。这些差异具有统计学意义，在6岁时变得明显。25岁以后脑重的下降率白人男性最高，其次是黑人女性、白人女性和黑人男性，除了白人男性和白人女性之间，其他差异无统计学意义。与早期报告相反，80岁以后脑重量迅速下降。在评估个体脑重时，将其与给定年龄的每个亚组的标准进行比较很重要。
