Judson F N, Penley K A, Robinson M E, Smith J K
Am J Epidemiol. 1980 Dec;112(6):836-43. doi: 10.1093/oxfordjournals.aje.a113056.
This study compared prevalence rates of most common sexually transmitted diseases (STD) in heterosexual and homosexual men who made respectively 12,201 and 5324 visits to an STD clinic over 18 months. Overall, homosexual men were significantly (p < 0.001) more likely than heterosexual men to have gonorrhea (30.31% vs. 19.83%), early syphilis (1.08% vs. 0.34%) and anal warts (2.90% vs. 0.26%) but less likely to have nongonococcal urethritis (NGU) (14.63% vs. 36.40%, p < 0.001), herpes genitalis (0.93% vs. 3.65%, p < 0.001), pediculosis pubis (4.30% vs. 5.35%, p < 0.005), scabies (0.42% vs. 0.76%, p < 0.02), and genital warts (1.68% vs. 6.69%, p < 0.001). In most cases the differences in rates remained significant (p < 0.05) when corrected for age and race. It is speculated that higher rates of gonorrhea and syphilis result from a larger mean number of sexual contacts, more potential sites of infection, and more hidden and asymptomatic disease, while the lower rates of the other STD result from a lesser susceptibility of anal mucosa to the causative agent(s) of NGU, herpes genitalis, and venereal warts or from a lack of pubic apposition (pediculosis pubis).
本研究比较了异性恋男性和同性恋男性中最常见性传播疾病（STD）的患病率，在18个月内，他们分别有12201次和5324次前往性病诊所就诊。总体而言，同性恋男性患淋病（30.31%对19.83%）、早期梅毒（1.08%对0.34%）和肛门疣（2.90%对0.26%）的可能性显著高于异性恋男性（p<0.001），但患非淋菌性尿道炎（NGU）（14.63%对36.40%，p<0.001）、生殖器疱疹（0.93%对3.65%，p<0.001）、阴虱病（4.30%对5.35%，p<0.005）、疥疮（0.42%对0.76%，p<0.02）和尖锐湿疣（1.68%对6.69%，p<0.001）的可能性较低。在大多数情况下，校正年龄和种族后，患病率差异仍具有显著性（p<0.05）。据推测，淋病和梅毒患病率较高是由于平均性接触次数较多、潜在感染部位较多以及更多隐匿和无症状疾病，而其他性传播疾病患病率较低是由于肛门黏膜对NGU、生殖器疱疹和尖锐湿疣病原体的易感性较低或由于缺乏耻骨贴合（阴虱病）。
