Abraha Million, Egli-Gany Dianne, Low Nicola
Institute of Social and Preventive Medicine, University of Bern, Finkenhubelweg 11, 3012 Bern, Switzerland.
F1000Res. 2018 Mar 27;7:400. doi: 10.12688/f1000research.13600.1. eCollection 2018.
Antimicrobial-resistant is a global public health problem in the 21st century. has developed resistance to all classes of antibiotics used for empirical treatment, and clinical treatment failure caused by extensively resistant strains has been reported. Identifying specific factors associated with an increased risk of antimicrobial-resistant might help to develop strategies to improve antimicrobial stewardship. In this review, we describe the findings of 24 studies, published between 1989 and 2017, that examined epidemiological, behavioural, and clinical factors and their associations with a range of antimicrobial agents used to treat gonorrhoea. Antimicrobial-resistant is more common in older than younger adults and in men who have sex with men compared with heterosexual men and women. Antimicrobial-resistant is less common in some black minority and Aboriginal ethnic groups than in the majority white population in high-income countries. The factors associated with antimicrobial-resistant gonorrhoea are not necessarily those associated with a higher risk of gonorrhoea.
耐抗菌药物是21世纪的一个全球公共卫生问题。[病原体名称]已对用于经验性治疗的所有类别的抗生素产生耐药性,并且已经报道了由广泛耐药菌株引起的临床治疗失败。确定与耐抗菌药物风险增加相关的具体因素可能有助于制定改善抗菌药物管理的策略。在本综述中,我们描述了1989年至2017年间发表的24项研究的结果,这些研究调查了流行病学、行为和临床因素及其与一系列用于治疗淋病的抗菌药物的关联。耐抗菌药物在老年人中比年轻人中更常见,在与男性发生性行为的男性中比异性恋男性和女性中更常见。在高收入国家,一些少数族裔黑人和原住民群体中的耐抗菌药物情况比多数白人人口中更少见。与耐抗菌药物淋病相关的因素不一定是与淋病高风险相关的因素。