阿司匹林对小鼠小肠黏膜的影响。超微结构研究。
The effect of aspirin on mouse small-intestinal mucosa. Ultrastructural studies.
作者信息
Djaldetti M, Fishman P
出版信息
Arch Pathol Lab Med. 1981 Mar;105(3):144-7.
PMID:6894078
Abstract
The ultrastructural alterations in the small-intestinal mucosa of mice given aspirin for five weeks were observed by light microscopy and scanning (SEM) and transmission (TEM) electron microscopy. The SEM examination revealed that the most affected areas were the duodenum and jejunum, which showed villous disarray, shortened microvilli with damaged tips, erosions, and an increased number of goblet cells. Similar findings were also observed with TEM.
摘要
通过光学显微镜、扫描电子显微镜（SEM）和透射电子显微镜（TEM）观察给予阿司匹林五周的小鼠小肠黏膜的超微结构改变。扫描电子显微镜检查显示，受影响最严重的区域是十二指肠和空肠，表现为绒毛紊乱、微绒毛缩短且顶端受损、糜烂以及杯状细胞数量增加。透射电子显微镜也观察到了类似的结果。
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