促吞噬素和D-精氨酸3-促吞噬素具有镇痛作用。
Tuftsin and D-Arg3-tuftsin possess analgesic action.
作者信息
Herman Z S, Stachura Z, Opiełka L, Siemion I Z, Nawrocka E
出版信息
Experientia. 1981 Jan 15;37(1):76-7. doi: 10.1007/BF01965580.
PMID:6894124
Abstract
Tuftsin has marked analgesic activity but is less potent than D-Arg3-tuftsin. The absence of an antagonistic effect of naloxone on tuftsin and its analogue suggests that these substances do not act on opiate receptors. Tuftsin and its analogues may represent a new class of substances of interest in the search for new analgesics.
摘要
促吞噬素具有显著的镇痛活性，但效力低于D-精氨酸3-促吞噬素。纳洛酮对促吞噬素及其类似物无拮抗作用，这表明这些物质不作用于阿片受体。促吞噬素及其类似物可能代表了一类在寻找新型镇痛药方面值得关注的新物质。
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