未处理小鼠及用3,5-二乙氧羰基-1,4-二氢可力丁处理的小鼠肝脏中N-甲基原卟啉IX的鉴定：甲基的来源 - Suppr

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超能文献

Identification of N-methylprotoporphyrin IX in livers of untreated mice and mice treated with 3, 5-diethoxycarbonyl- 1, 4-dihydrocollidine: source of the methyl group.

作者信息

Tephly T R, Coffman B L, Ingall G, Ziet-Har M S, Goff H M, Tabba H D, Smith K M

出版信息

Arch Biochem Biophys. 1981 Nov;212(1):120-6. doi: 10.1016/0003-9861(81)90350-7.

DOI:10.1016/0003-9861(81)90350-7

PMID:6895449

Abstract

摘要

相似文献

Identification of N-methylprotoporphyrin IX in livers of untreated mice and mice treated with 3, 5-diethoxycarbonyl- 1, 4-dihydrocollidine: source of the methyl group.未处理小鼠及用3,5-二乙氧羰基-1,4-二氢可力丁处理的小鼠肝脏中N-甲基原卟啉IX的鉴定：甲基的来源

Arch Biochem Biophys. 1981 Nov;212(1):120-6. doi: 10.1016/0003-9861(81)90350-7.

N-Alkylprotoporphyrin IX formation in 3,5-dicarbethoxy-1,4-dihydrocollidine-treated rats. Transfer of the alkyl group from the substrate to the porphyrin.3,5-二乙氧羰基-1,4-二氢可力丁处理的大鼠体内N-烷基原卟啉IX的形成。烷基从底物向卟啉的转移。

J Biol Chem. 1981 Jul 10;256(13):6708-13.

N-Methylprotoporphyrin IX: chemical synthesis and identification as the green pigment produced by 3,5-diethoxycarbonyl-1,4-dihydrocollidine treatment.N-甲基原卟啉IX：化学合成及鉴定为3,5-二乙氧基羰基-1,4-二氢可力丁处理产生的绿色色素

Proc Natl Acad Sci U S A. 1981 Mar;78(3):1490-4. doi: 10.1073/pnas.78.3.1490.

Stimulation of the pathway of porphyrin synthesis in the liver of rats and mice by griseofulvin, 3,5-Diethoxycarbonyl-1,4-dihydrocollidine and related drugs: evidence for two basically different mechanisms.灰黄霉素、3,5-二乙氧羰基-1,4-二氢可力丁及相关药物对大鼠和小鼠肝脏卟啉合成途径的刺激作用：两种根本不同机制的证据

Biochem J. 1975 Jan;146(1):285-7. doi: 10.1042/bj1460285.

Isolation of an N-alkylprotoporphyrin IX from chick embryo livers following the administration of 3,5-diethoxycarbonyl-1,4-dihydro-4-ethyl-2,6-dimethylpyridine.

Can J Physiol Pharmacol. 1987 Jul;65(7):1500-2. doi: 10.1139/y87-235.

The effect of beta-adrenergic blocking agents on experimental porphyria induced by 3,5-diethoxycarbonyl-1,4-dihydrocollidine (DDC) in vivo and in vitro.β-肾上腺素能阻滞剂对3,5-二乙氧羰基-1,4-二氢可力丁（DDC）体内外诱导的实验性卟啉病的影响。

Biochim Biophys Acta. 1976 Aug 24;444(1):286-93. doi: 10.1016/0304-4165(76)90245-2.

The formation of N-alkylprotoporphyrin IX and destruction of cytochrome P-450 in the liver of rats after treatment with 3,5-diethoxycarbonyl-1,4-dihydrocollidine and its 4-ethyl analog.

Arch Biochem Biophys. 1982 Oct 1;218(1):220-4. doi: 10.1016/0003-9861(82)90339-3.

Studies on the mechanism of experimental porphyria produced by 3,5-diethoxycarbonyl-1,4-dihydrocollidine. Role of a porphyrin-like inhibitor of protohaem ferro-lyase.3,5 - 二乙氧羰基 - 1,4 - 二氢可力丁所致实验性卟啉症机制的研究。一种原卟啉亚铁裂解酶的卟啉样抑制剂的作用。

Biochem J. 1979 Apr 15;180(1):241-4. doi: 10.1042/bj1800241.

Ferrochelatase-inhibitory activity and N-alkylprotoporphyrin formation with analogues of 3,5-diethoxycarbonyl-1,4-dihydro-2,4,6-trimethylpyridine (DDC) containing extended 4-alkyl groups: implications for the active site of ferrochelatase.含延长4-烷基的3,5-二乙氧羰基-1,4-二氢-2,4,6-三甲基吡啶（DDC）类似物的亚铁螯合酶抑制活性及N-烷基原卟啉的形成：对亚铁螯合酶活性位点的意义

Mol Pharmacol. 1986 Oct;30(4):352-7.

Inhibition of protohaem ferro-lyase in experimental porphyria. Isolation and partial characterization of a modified porphyrin inhibitor.实验性卟啉症中原卟啉铁裂解酶的抑制作用。一种修饰卟啉抑制剂的分离及部分特性鉴定。

Biochem J. 1980 Apr 15;188(1):145-52. doi: 10.1042/bj1880145.

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-Methyl Protoporphyrin IX: An Understudied Porphyrin.- 原卟啉 IX 甲酯：一种研究不足的卟啉。

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Porphyrin-Induced Protein Oxidation and Aggregation as a Mechanism of Porphyria-Associated Cell Injury.卟啉诱导的蛋白氧化和聚集作为卟啉病相关细胞损伤的机制。

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"Toxic memory" via chaperone modification is a potential mechanism for rapid Mallory-Denk body reinduction.通过伴侣蛋白修饰产生的“毒性记忆”是Mallory-Denk小体快速重现的一种潜在机制。

Hepatology. 2008 Sep;48(3):931-42. doi: 10.1002/hep.22430.

Intermediate filament cytoskeleton of the liver in health and disease.健康与疾病状态下肝脏的中间丝细胞骨架

Histochem Cell Biol. 2008 Jun;129(6):735-49. doi: 10.1007/s00418-008-0431-x. Epub 2008 Apr 29.

Cytokeratin 8 protects from hepatotoxicity, and its ratio to cytokeratin 18 determines the ability of hepatocytes to form Mallory bodies.细胞角蛋白8可保护细胞免受肝毒性影响，其与细胞角蛋白18的比例决定了肝细胞形成马洛里小体的能力。

Am J Pathol. 2000 Apr;156(4):1263-74. doi: 10.1016/S0002-9440(10)64997-8.

Formation of N-methyl protoporphyrin in chemically-induced protoporphyria. Studies with a novel porphyrogenic agent.

Arch Toxicol. 1993;67(3):179-85. doi: 10.1007/BF01973305.

The use of N-methylprotoporphyrin dimethyl ester to inhibit ferrochelatase in Rhodopseudomonas sphaeroides and its effect in promoting biosynthesis of magnesium tetrapyrroles.使用N-甲基原卟啉二甲酯抑制球形红假单胞菌中的亚铁螯合酶及其对促进四吡咯镁生物合成的作用。

Biochem J. 1982 Nov 15;208(2):479-86. doi: 10.1042/bj2080479.

The effect of N-methylprotoporphyrin IX on the synthesis of photosynthetic pigments in Cyanidium caldarium. Further evidence for the role of haem in the biosynthesis of plant billins.N-甲基原卟啉IX对嗜热栖热放线菌光合色素合成的影响。血红素在植物胆色素生物合成中作用的进一步证据。

Biochem J. 1982 Nov 15;208(2):487-91. doi: 10.1042/bj2080487.

Ferrochelatase activity in the photosynthetic alga Cyanidium caldarium. Development of the enzyme during biosynthesis of photosynthetic pigments.光合藻类蓝纤维藻中的亚铁螯合酶活性。光合色素生物合成过程中该酶的发育。

Biochem J. 1984 Jun 15;220(3):861-3. doi: 10.1042/bj2200861.

Ferrochelatase and N-alkylated porphyrins.亚铁螯合酶与N-烷基化卟啉

Mol Cell Biochem. 1984 Sep;64(2):127-37. doi: 10.1007/BF00224769.

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