Delides G S, Garas G, Georgouli G, Jiortziotis D, Lecca J, Liva T, Elemenoglou J
Arch Pathol Lab Med. 1982 Mar;106(3):126-8.
To assess the reliability of the World Health Organization's grading system for breast carcinomas, six observers independently graded 158 tumors. Five of the observers had been simultaneously trained in the same institution. The sixth was one of their tutors. There was agreement in the grading of only 23 cases, most of which were either well or poorly differentiated tumors. If the prognosis breast carcinoma is predicated by the who method, it should be restricted to the two extreme groups. It seems that there is no need to apply the who grading method because these groups could be easily distinguished by the overall impression of the examining pathologists.
为评估世界卫生组织乳腺癌分级系统的可靠性，六名观察者对158例肿瘤进行了独立分级。其中五名观察者在同一机构同时接受培训。第六名观察者是他们的一名导师。仅在23例病例的分级上达成了一致，其中大多数是高分化或低分化肿瘤。如果用世界卫生组织的方法预测乳腺癌的预后，应该仅限于两个极端组。似乎没有必要应用世界卫生组织的分级方法，因为通过检查病理学家的总体印象就可以很容易地区分这些组。
