Meena Sudha Pankaj, Hemrajani Deepika K, Joshi Narayani
Department of Pathology, SMS Medical College, Jaipur.
Indian J Pathol Microbiol. 2006 Apr;49(2):199-202.
Breast carcinoma is one of the leading causes of malignancy in females. Diagnosis of breast carcinoma is often made by fine needle aspiration biopsy. Nuclear grading is the most important prognostic factor. It is important to grade the breast carcinoma which will provide valuable information to the treating oncologist to plan the management. The purpose of the study is to compare the cytological grading with histological grading and to assess the prognosis according to the grade. 100 cases of breast carcinoma were graded cytologically by Robinson Grading system and 71 cases were graded histologically by modified Bloom-Richardson system and results of both were compared and statistical correlation was done. In the present study sensitivity and specificity of cytological grading system were 90.77% and 84.42% respectively.
乳腺癌是女性恶性肿瘤的主要原因之一。乳腺癌的诊断通常通过细针穿刺活检进行。核分级是最重要的预后因素。对乳腺癌进行分级很重要，这将为治疗肿瘤学家制定治疗方案提供有价值的信息。本研究的目的是比较细胞学分级与组织学分级，并根据分级评估预后。对100例乳腺癌病例采用罗宾逊分级系统进行细胞学分级，对71例病例采用改良的布鲁姆-理查森系统进行组织学分级，比较两者结果并进行统计学相关性分析。在本研究中，细胞学分级系统的敏感性和特异性分别为90.77%和84.42%。
