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子宫颈玻璃样细胞癌。超微结构研究及文献复习。

Glassy cell carcinoma of the uterine cervix. An ultrastructural study and review.

作者信息

Zaino R J, Nahhas W A, Mortel R

出版信息

Arch Pathol Lab Med. 1982 May;106(5):250-4.

PMID:6896138
Abstract

Glassy cell carcinoma is an unusual neoplasm of the uterine cervix that accounts for 1% to 2% of all cervical malignant neoplasms. Although it seems to have a distinct histologic appearance, it has generally not been recognized, as indicated by the extremely small number of cases reported in the literature. Previous studies have indicated an aggressive behavior, a poor response to irradiation and surgery, and a tendency to widespread metastases. It occurs in a younger age group (mean age, 41 years) than other cervical neoplasms and often has been associated with pregnancy. The histogenesis is not known, but electron microscopic examination of one case we studied, and review of one previously described case, demonstrate that it is an adenosquamous carcinoma. The need to define this neoplasm better will be satisfied only by additional, thorough histologic and clinical studies.

摘要

玻璃样细胞癌是一种不常见的子宫颈肿瘤,占所有宫颈恶性肿瘤的1%至2%。尽管它似乎具有独特的组织学表现,但如文献报道的病例极少所示,它通常未被认识到。先前的研究表明其具有侵袭性、对放疗和手术反应不佳以及有广泛转移的倾向。它比其他宫颈肿瘤发生在更年轻的年龄组(平均年龄41岁),并且常与妊娠有关。其组织发生尚不清楚,但我们研究的一例以及回顾先前描述的一例的电子显微镜检查表明它是一种腺鳞癌。只有通过更多深入的组织学和临床研究才能满足更好地界定这种肿瘤的需求。

相似文献

1
Glassy cell carcinoma of the uterine cervix. An ultrastructural study and review.子宫颈玻璃样细胞癌。超微结构研究及文献复习。
Arch Pathol Lab Med. 1982 May;106(5):250-4.
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Villous adenoma of the uterine cervix associated with invasive adenocarcinoma: a histologic, ultrastructural, and immunohistochemical study.宫颈绒毛状腺瘤伴浸润性腺癌:一项组织学、超微结构及免疫组织化学研究
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Glassy cell carcinoma of the uterine cervix.子宫颈玻璃样细胞癌。
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Diagn Gynecol Obstet. 1981 Spring;3(1):31-8.
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Glassy cell carcinoma of the uterine cervix a rare histology. Report of three cases with a review of the literature.子宫颈玻璃样细胞癌是一种罕见的组织学类型。三例病例报告并文献复习。
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引用本文的文献

1
RETRACTED ARTICLE: Cervical adenosquamous carcinoma: detailed analysis of morphology, immunohistochemical profile, and clinical outcomes in 59 cases.撤回文章:宫颈腺鳞癌:59 例形态学、免疫组织化学特征及临床转归的详细分析。
Mod Pathol. 2019 Feb;32(2):269-279. doi: 10.1038/s41379-018-0123-6. Epub 2018 Sep 26.
2
A novel human glassy-cell carcinoma cell line producing IL-6 and IL-8 from uterine cervix.一种源自子宫颈、可产生白细胞介素-6和白细胞介素-8的新型人玻璃样细胞癌细胞系。
In Vitro Cell Dev Biol Anim. 1998 Apr;34(4):290-7. doi: 10.1007/s11626-998-0005-1.